Cures by Design
Cyrus Bio is a computationally-driven discovery company focused on naturally existing proteins that show the potential to be turned into superior therapeutics using computational modeling and deep mutagenesis.
- Proven platform – 30+ discovery programs with partners
- Rapid path to superior biologics engineered from natural proteins
- Integrated approach to protein design employing novel algorithms and sophisticated laboratory methods
- Lead programs in severe autoimmune disease and therapeutic immuno cytokines
IdeS: IgG Depletion for Auto-Immune Diseases
Cyrus IdeS uniquely addresses over $20B of clinical market in IgG-driven autoimmune disease such as gMG and ITP.
A Potent IL-22 Variant for Autoimmune Gastrointestinal and Metabolic Indications
Cyrus IL-22 fusion protein enables superior efficacy via disinhibition against naturally occurring IL-22 Binding Protein.
ACE2v2-Fc Half-life Optimized ARDS Candidate
Cyrus’ ACE2v2 is an optimized ACE2-IgG Fc fusion protein that has been engineered for extended PK and pharmacology using our protein design and glycosylation platforms for treatment of Acute Respiratory Distress Syndrome.